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COX-1-IN-3

" in MedChemExpress (MCE) Product Catalog:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-W009347
    COX-1-IN-3

    		COX Inflammation/Immunology
    COX-1-IN-3 (compound 19) is a COX-1 inhibitor with non-steroidal anti-inflammatory activity .
    COX-1-IN-3
  • HY-181602
    ATP Synthesis-IN-4

    		ATP Synthase COX Oxidative Phosphorylation AMPK Cancer
    ATP Synthesis-IN-4 is a mitochondria-targeted small-molecule ligand that inhibits ATP synthesis. ATP Synthesis-IN-4 binds to mtDNA G4s in melanoma cells, thereby inducing changes in mitochondrial metabolism and inhibiting cell proliferation. ATP Synthesis-IN-4 suppresses the translation of key mitochondrial respiratory chain proteins (CYTB, ATP8, COX1, COX3, ND2) in melanoma cells, downregulates the expression of OXPHOS complexes, activates the phosphorylation of AMPK, and induces metabolic reprogramming to upregulate glycolysis. ATP Synthesis-IN-4 is applicable to relevant research on melanoma .
    ATP Synthesis-IN-4

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