1 Result for "

CYP51-IN-20

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CYP51-IN-20" in MCE Product Catalog:

Cat. No.: HY-159585
Target:  

Cytochrome P450 Fungal

Research Areas:  

Infection

CYP51-IN-20 (compound 5b) is an inhibitor of CYP51 and has antifungal activity. CYP51-IN-20 has a significant inhibitory effect on Candida albicans ATCC 10231, downregulates ERG11 (Cyp51) gene expression, and significantly reduces the yeast-to-hyphae morphological transition. CYP51-IN-20 can synergize with Voriconazole (HY-76200) to occupy the entire CYP51 binding site and exert a synergistic inhibitory effect in the Glechoma moth model .
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