2 Results for "

Carassius auratus

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Carassius auratus" in MCE Product Catalog:

NSC 90469
NSC 90469
0 Images
Cat. No.: HY-114557
CAS No.: 1041-01-6
Purity:  99.38%
Synonyms: 3,5-Diiodo-L-thyronine
Category:  

Monophenols Ketones, Aldehydes, Acids Metabolic Disease Phenols Endogenous metabolite Disease Research Fields

Target:  

JNK NF-κB Sirtuin PGC-1α COX TGF-β Receptor Collagen

NSC 90469 (3,5-Diiodo-L-thyronine) is an orally active thyroid hormone derivative. NSC 90469 inhibits JNK phosphorylation and NF-κB acetylation, blocks SIRT1 protein expression, induces elevated PGC-1α levels, and stimulates COX activity. NSC 90469 enhances UCP1-mediated thermogenesis, increases hepatic Dio1 activity, inhibits TSH levels and hypothalamic-pituitary-thyroid axis function, enhances lipid metabolism, and regulates energy metabolism via the mitochondrial pathway. NSC 90469 prevents blood glucose reduction, reduces urinary albumin excretion, inhibits renal matrix expansion, decreases TGF-β1 expression, and reduces renal fibronectin and type Ⅳ collagen deposition. NSC 90469 also increases energy expenditure and prevents diet-induced overweight. NSC 90469 can be used in studies related to diabetic nephropathy, hypothyroidism, non-alcoholic fatty liver disease, and diet-induced obesity .
loading...
    loading...
View All Sizes
Leptin Protein, Carassius auratus (P.pastoris, His)
Leptin Protein, Carassius auratus (P.pastoris, His)
0 Images
Cat. No.: HY-P70181
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LEP; Leptin (Murine Obesity Homolog); Prev. OBS; Obese Protein; Prev. OB; Obese, Mouse, Homolog Of; Obesity Factor; LEPD; Leptin; Leptin (Obesity Homolog, Mouse)
Species:  
Others
Source:  
P. pastoris
loading...
    loading...
View All Sizes
Assay Types