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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
464 Results for "
Cross-linker
" in MedChemExpress (MCE) Product Catalog:
Products (464)
464 Results for "Cross-linker" in MCE Product Catalog:
837
837 Publications Verification
Cat. No.: HY-17394
CAS No.: 15663-27-1
Synonyms: cis-Platinum; CDDP; cis-Diaminodichloroplatinum
연구분야:
Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
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Target:
Busulfan is a potent alkylating antineoplastic agent. Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic agent .
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16 Cited Publications
Cat. No.: HY-W019543
CAS No.: 68528-80-3
연구분야:
Disuccinimidyl suberate Crosslinker is an amine-reactive bifunctional protein crosslinker. Disuccinimidyl suberate Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
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13 Cited Publications
Cat. No.: HY-K0218A
MCE Streptavidin Agarose 6FF, a 6% highly cross-linked agarose reagent coupled with recombinant streptavidin, is an affinity chromatography medium for separation and purification of biotinylated peptides, antibodies, lectins, etc. The total binding capacity of Streptavidin Agarose 6FF is more than 200 nmol of D-Biotin/mL settled resin.
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9 Cited Publications
Synonyms: EGS Crosslinker
Target:
연구분야:
EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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8 Cited Publications
Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione
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연구분야:
Tesirine (SG3249) is an antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 (HY-101161) is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity .
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Target:
Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties .
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6 Cited Publications
Synonyms: SDX-105 free base
Target:
Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties .
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5 Cited Publications
Synonyms: Disuccinimidyl glutarate
Target:
연구분야:
DSG Crosslinker is an amine-reactive and noncleavable protein crosslinker. DSG Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
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5 Cited Publications
Synonyms: SPDP Crosslinker; Py-ds-Prp-OSu
Target:
연구분야:
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
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5 Cited Publications
Cat. No.: HY-D0975
CAS No.: 92921-24-9
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4 Cited Publications
Synonyms: (S)-2-Pyridylthio Cysteamine Hydrochloride
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3 Cited Publications
Target:
연구분야:
BS3 Crosslinker is an amine-reactive homobifunctional protein crosslinker. BS3 Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
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3 Cited Publications
Target:
연구분야:
DSP Crosslinker is an amine-reactive and cleavable protein crosslinker. DSP Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
