1. Antibody-drug Conjugate/ADC Related
  2. ADC Linkers
  3. DSG Crosslinker

DSG Crosslinker 

Cat. No.: HY-114697 Purity: 99.39%
Handling Instructions

DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

DSG Crosslinker Chemical Structure

DSG Crosslinker Chemical Structure

CAS No. : 79642-50-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 88 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 88 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
50 mg USD 230 In-stock
Estimated Time of Arrival: December 31
100 mg USD 390 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

326.26

Formula

C13H14N2O8

CAS No.
SMILES

O=C(CCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (306.50 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0650 mL 15.3252 mL 30.6504 mL
5 mM 0.6130 mL 3.0650 mL 6.1301 mL
10 mM 0.3065 mL 1.5325 mL 3.0650 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.39%

References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
DSG Crosslinker
Cat. No.:
HY-114697
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