1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. DSP Crosslinker

DSP Crosslinker 

Cat. No.: HY-118759 Purity: 98.04%
Handling Instructions

DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

DSP Crosslinker Chemical Structure

DSP Crosslinker Chemical Structure

CAS No. : 57757-57-0

Size Price Stock Quantity
100 mg USD 85 In-stock
Estimated Time of Arrival: December 31
250 mg USD 170 In-stock
Estimated Time of Arrival: December 31
500 mg USD 290 In-stock
Estimated Time of Arrival: December 31
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

404.42

Formula

C₁₄H₁₆N₂O₈S₂

CAS No.

57757-57-0

SMILES

O=C(CCSSCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (618.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4727 mL 12.3634 mL 24.7268 mL
5 mM 0.4945 mL 2.4727 mL 4.9454 mL
10 mM 0.2473 mL 1.2363 mL 2.4727 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

DSP CrosslinkerADC LinkerAntibody-drug conjugates linkercleavableADClinkerInhibitorinhibitorinhibit

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Product Name:
DSP Crosslinker
Cat. No.:
HY-118759
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