106 Results for "

Crystal

" in MedChemExpress (MCE) Product Catalog:
Products (106)

106 Results for "Crystal" in MCE Product Catalog:

65
Crystal Violet
Crystal Violet
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65 Publications Verification
製品番号: HY-B0324A
CAS 番号: 548-62-9
別名: Basic Violet 3; Gentian Violet; Methyl Violet 10B
Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1].
22
Lithium stearate
Lithium stearate
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22 Cited Publications
製品番号: HY-W099571
CAS 番号: 4485-12-5
別名: Stearic acid lithium; Lithium octadecanoate
Target:  

Environmental Pollutants Biochemical Assay Reagents

研究分野:  

Others

Lithium stearate (Stearic acid (lithium)) is a compound that forms vesicles in reaction with silver nitrate, thereby changing the reaction kinetics of the nucleation and self-assembly process of silver stearate. It has the activity that even in the presence of excess silver nitrate, only about 80% can be converted into silver stearate and the residual lithium stearate will inhibit the growth process of silver stearate crystals, thereby producing silver stearate crystals that are much smaller than those obtained from sodium stearate, providing an opportunity to further control the self-assembly and crystal growth of silver stearate.
2
Cichoriin
Cichoriin
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2 Cited Publications
製品番号: HY-N8599
CAS 番号: 531-58-8
Category:  

Infection other families Monophenols Coumarins Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

Amylases Glycosidase Lipase Dipeptidyl Peptidase p38 MAPK PPAR P2Y Receptor NOD-like Receptor (NLR) SARS-CoV Pyroptosis GLUT Angiotensin-converting Enzyme (ACE) NF-κB

Cichoriin is an orally active coumarin glycoside with broad biological activities. Cichoriin exhibits inhibitory activities against α-amylase, α-glucosidase, pancreatic lipase and DPP-IV, with IC50 values of 5.76, 2.94, 16.83 and 9.16 μg/mL, respectively. Cichoriin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) in mice by activating the AMPK signaling pathway. Cichoriin upregulates PPAR-γ in adipose tissue and alleviates obesity and associated cardiorenal injury in rats. Cichoriin blocks monosodium urate crystal-induced activation of the NLRP3 inflammasome and cell pyroptosis by inhibiting P2Y14R (IC50 = 8.47 nM). In silico virtual screening reveals that Cichoriin has a strong binding affinity for SARS-CoV-2 .
2
Djenkolic acid
Djenkolic acid
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2 Cited Publications
製品番号: HY-125923
CAS 番号: 498-59-9
純度:  ≥98.0%
Category:  

other families Metabolic Disease Amino acids Plants Disease Research Fields Archidendron jiringa

Target:  

Bacterial

Djenkolic acid is a sulfur-containing amino acid. Djenkolic acid can be isolated from the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic acid de-inhibits the SO4 2- uptake system in Pseudomonas fluorescens. Djenkolic acid causes supersaturation of the urinary system with djenkolic acid crystals, leading to urinary tract obstruction and acute kidney injury .
2
Pectolinarigenin
Pectolinarigenin
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2 Cited Publications
製品番号: HY-N0493
CAS 番号: 520-12-7
Category:  

Flavonoids Flavones Campylotropis hirtella (Franch.) Schindl. Phenols Polyphenols Plants Compositae Disease Research Fields Inflammation/Immunology

Target:  

COX Lipoxygenase NF-κB p38 MAPK ERK HIF/HIF Prolyl-Hydroxylase Keap1-Nrf2 PI3K Apoptosis Autophagy

Pectolinarigenin is an orally active dual inhibitor of COX-2/5-LOX with anti-inflammatory, antioxidant, antitumor and neuroprotective activities. Pectolinarigenin exerts neuroprotective and anti-inflammatory effects on astrocyte inflammation via the NFκB and MAPK pathways. Pectolinarigenin inhibits LPS-induced phosphorylation of ERK1/2, N-FκB and p38MAPK, directly inhibits the enzymatic activity or binding of COX-2, 5-LOX and HIF-1α, and reduces the level of XIAP. Pectolinarigenin modifies Keap1 to promote nuclear accumulation of Nrf2, induces ARE-mediated antioxidant enzyme expression, and possesses direct free radical scavenging activity. Pectolinarigenin reduces the release of NO, proinflammatory mediators and leukotrienes, and increases the level of IL-10. Pectolinarigenin induces G2/M cell cycle arrest, apoptosis (Apoptosis) and autophagy (Autophagy) via the PI3K/AKT/mTOR signaling pathway. Pectolinarigenin reduces renal crystal deposition and inhibits melanin synthesis. Pectolinarigenin inhibits inflammation and alleviates allergy in mouse models of inflammation. Pectolinarigenin alleviates renal injury, inflammation and oxidative stress in mice by inhibiting HIF-1α activity. Pectolinarigenin can be used for the research of neurodegenerative diseases, inflammatory/allergic diseases, calcium oxalate nephrocalcinosis, gastric cancer, melasma, post-inflammatory diseases and chloasma .
1
Medronic acid
Medronic acid
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1 Cited Publications
製品番号: HY-108309
CAS 番号: 1984-15-2
純度:  ≥98.0%
別名: Methylenediphosphonic acid
Target:  

Biochemical Assay Reagents

研究分野:  

Others

Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis .
1
Icomidocholic acid
Icomidocholic acid
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1 Cited Publications
製品番号: HY-19796
CAS 番号: 246529-22-6
別名: Aramchol; C20-FABAC
Target:  

Stearoyl-CoA Desaturase (SCD)

研究分野:  

Metabolic Disease

Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) .
1
Erlose
Erlose
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1 Cited Publications
製品番号: HY-139338
CAS 番号: 13101-54-7
純度:  ≥99.0%
Category:  

Polysaccharides Animals Other Diseases Disease Research Fields Sweeteners Saccharides Food Research

Target:  

Glycosidase

Erlose is a trisaccharide sucrose derivative and low-calorie sweetener synthesized from glucose and sucrose via an α-glucosidase-mediated transglycosylation reaction. Erlose is often used as a marker to identify whether honey is adulterated with artificial sucrose. Erlose has approximately half the sweetness of sucrose but a similar taste, and it effectively inhibits crystal formation and browning reactions during food heat treatment .
1
Rasburicase
Rasburicase
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1 Cited Publications
製品番号: HY-108844
CAS 番号: 134774-45-1
純度:  95.00%
Category:  

天然物 Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Xanthine Oxidase

Rasburicase is a recombinant form of urate oxidase that works by catalyzing the oxidation of uric acid to allantoin, which has a higher solubility. Rasburicase specifically degrades uric acid, rapidly lowers blood uric acid levels, and improves inflammation and kidney damage caused by uric acid crystal deposition. Rasburicase can effectively lower uric acid and prevent uric acid nephropathy, and is used in the study of severe hyperuricemia associated with tumor lysis syndrome (TLS) and refractory gout .
Fmoc-leucine
Fmoc-leucine
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製品番号: HY-101064
CAS 番号: 35661-60-0
純度:  99.89%
別名: N-FMOC-leucine; NPC 15199; NSC 334290
Target:  

PPAR Calcium Channel Lipase

研究分野:  

Metabolic Disease Inflammation/Immunology

Fmoc-Leucine (N-FMOC-leucine) is an anti-inflammatory agent that not only promotes extracellular Ca 2+ influx but also facilitates intracellular Ca 2+ release. Fmoc-Leucine is a selective ligand for PPARγ (Ki = 15 μM), exhibiting insulin-sensitizing effects but with weak fatogenic activity. Fmoc-Leucine exhibits unique self-assembly properties and can form transient gels, stable gels, or crystals/2D sheets through different pathways. Fmoc-Leucine can be used in the research of diabetes, colitis, and bladder cancer .
Sodium formate
Sodium formate
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製品番号: HY-W088065
CAS 番号: 141-53-7
Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD50=7410 mg/kg and acute intravenous LD50=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .
Glycerol dioleate
Glycerol dioleate
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製品番号: HY-154487
CAS 番号: 25637-84-7
Target:  

Biochemical Assay Reagents

研究分野:  

Neurological Disease

Glycerol dioleate is a lipid capable of forming Lyotropic Liquid Crystal (LLC). When formulated with phosphatidylcholine and exposed to aqueous media, glycerol dioleate constructs an inverted hexagonal (HII) phase structure with sustained-release properties. The in-situ forming gel prepared by optimizing glycerol dioleate with phosphatidylcholine and N-methyl-2-pyrrolidone enables stable release of Risperidone (HY-11018) for up to 60 days in vitro and in vivo. Glycerol dioleate causes minimal side effects in rabbits, making it an ideal carrier component for the development of antischizophrenia agents .Note: Lyotropic liquid crystals (Lyotropic Liquid Crystal, LLC) are ordered fluid phases self-assembled by amphipathic molecules (e.g., lipids, surfactants) in solvents (usually water) at specific concentrations .
α-Lactose hydrate
α-Lactose hydrate
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製品番号: HY-W087904
CAS 番号: 5989-81-1
別名: α-D-Lactose hydrate
Category:  

Polysaccharides Animals Saccharides

Target:  

Endogenous Metabolite Biochemical Assay Reagents

α-Lactose hydrate (α-D-Lactose (hydrate)) is the primary carbohydrate in the milk of most mammals. α-Lactose hydrate consists of glucose and galactose and exists in two isomeric forms, α and β. α-Lactose hydrate has numerous applications in the food and pharmaceutical industries, such as serving as a bulking or agglomerating agent, and a diluent for pigments, flavors or enzymes .
Polyvinylpyrrolidone K90
Polyvinylpyrrolidone K90
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製品番号: HY-B1620H
CAS 番号: 9003-39-8
別名: PVP K90; Polyvidone K90; Povidone K90
Polyvinylpyrrolidone K90 can be used to prepare drug delivery systems, such as electrospun nanofibrous membranes. Polyvinylpyrrolidone K90 is widely used in human and veterinary medicine as an effective wound healing promoter and disinfectant when combined with iodine and other compounds. In addition, Polyvinylpyrrolidone K90 is also used to stabilize nanosuspensions, interact with the surface of drug crystals, and remain bound to the surface after drying .
Bis-​PEG4-​NHS ester
Bis-​PEG4-​NHS ester
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製品番号: HY-130086
CAS 番号: 1314378-11-4
純度:  99.29%
Target:  

ADC Linkers

研究分野:  

Cancer

Bis-PEG4-NHS ester is a crosslinking reagent and amine-reactive modulator .Bis-PEG4-NHS ester reacts with primary amine groups on liposome surfaces via amide bond formation to covalently attach dibenzylcyclooctyne groups, with a hydrophilic PEG4 spacer reducing steric hindrance for subsequent click chemistry .Bis-PEG4-NHS ester enables site-specific antibody coupling to liposome surfaces via copper-free strain-promoted alkyne-azide cycloaddition click chemistry without disrupting liposome structure in minimal organic solvent volumes .Bis-PEG4-NHS ester undergoes hydrolysis during annealing to form -COOH groups that interact with PbI and FAI to enhance perovskite structural integrity, passivate defects, and modulate nucleation kinetics to regulate crystal growth .Bis-PEG4-NHS ester enhances device efficiency and long-term stability when used as an antisolvent additive for p-i-n perovskite solar cells .
Pigment Yellow 139
Pigment Yellow 139
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製品番号: HY-D0284
CAS 番号: 36888-99-0
Pigment Yellow 139 is a biological dye and indicator. Pigment Yellow 139 is an organic pigment and an additive for color filters of liquid crystal displays. When formulated in a dye-pigment hybrid system, Pigment Yellow 139 can form color filters with specific chromaticity coordinates, brightness, contrast, and average particle size .
Crystal violet, IND (0.0-2.0)
Crystal violet, IND (0.0-2.0)
0 Images
製品番号: HY-W110794
CAS 番号: 548-62-9
Crystal violet, IND (0.0-2.0) is a specialized indicator suitable for strongly acidic systems, which reflects changes in pH within the range of 0.0-2.0 through color changes. Crystal violet, IND (0.0-2.0) is widely used in acid-base titration, chemical analysis, and industrial testing fields .
Crystal Violet (solution)
Crystal Violet (solution)
0 Images
製品番号: HY-DY2001
CAS 番号: 548-62-9
Crystal Violet (solution) , also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining .
Solvent and Concentration: Sterile water: 5 mg/mL (0.5%)
Alizarin complexone
Alizarin complexone
0 Images
製品番号: HY-121075
CAS 番号: 3952-78-1
純度:  ≥98.0%
Target:  

Fluorescent Dye Reverse Transcriptase HIV RSV

研究分野:  

Infection Endocrinology Cancer

Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .
Sodium polyphosphate, crystal,+200 mesh, 96%
Sodium polyphosphate, crystal,+200 mesh, 96%
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製品番号: HY-W111692
CAS 番号: 68915-31-1
Sodium polyphosphate, crystal,+200 mesh, 96% is an inorganic polyphosphate that also serves as a stabilizer, dispersant, chelating agent, and coacervate-forming agent. Sodium polyphosphate provides electrostatic stabilization for mineral and material suspensions, but its dispersing efficacy decreases under acidic pH, high temperature, high calcium concentration, or a combination of these conditions. Sodium polyphosphate can chelate alkaline earth metals, reduce solution pH, and alter the rate of pH decline at a divalent cation/phosphorus molar ratio of 0.18. Sodium polyphosphate forms coacervates with smaller divalent cations and precipitates with larger divalent cations, where the functional requirements of cations depend on polyphosphate concentration, average degree of polymerization, and cation type .
Assay Types