7 Results for "

Cyclic GMP (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Cyclic GMP (Standard)" in MCE Product Catalog:

Cyclic GMP (Standard)
Cyclic GMP (Standard)
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Cat. No.: HY-113469R
CAS No.: 7665-99-8
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite

Target:  

Endogenous Metabolite Reference Standards

Cyclic GMP (Standard) is the analytical standard of Cyclic GMP (HY-113469). This product is intended for research and analytical applications. Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
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Guanosine (Standard)
Guanosine (Standard)
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Cat. No.: HY-N0097R
CAS No.: 118-00-3
Synonyms: DL-Guanosine (Standard); Vernine (Standard)
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Immune System Disorder Disease markers Endocrine diseases Endogenous metabolite

Target:  

Reference Standards HSV Endogenous Metabolite

Guanosine (Standard) is the analytical standard of Guanosine. This product is intended for research and analytical applications. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity. In Vitro: Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP).
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3-Methylxanthine (Standard)
3-Methylxanthine (Standard)
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Cat. No.: HY-50723R
CAS No.: 1076-22-8
Category:  

Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Reference Standards Endogenous Metabolite Phosphodiesterase (PDE) Caspase Bcl-2 Family Apoptosis

3-Methylxanthine (Standard) is the analytical standard of 3-Methylxanthine. This product is intended for research and analytical applications. 3-Methylxanthine is a blood-brain barrier-permeable cyclic GMP phosphodiesterase inhibitor, with an IC50 of 920 μM against guinea pig cyclic GMP phosphodiesterase. 3-Methylxanthine relaxes the spontaneous tension of isolated guinea pig tracheal smooth muscle preparations. Through a DRD1-dependent pathway, 3-Methylxanthine upregulates the expression of γH2AX and activated caspase-3, downregulates the expression of Bcl-2, and enhances Cisplatin-induced apoptosis (apoptosis) in ovarian cancer cells both in vitro and in vivo. 3-Methylxanthine induces clonic convulsions in the central nervous system. 3-Methylxanthine is the major metabolite of Theophylline (HY-B0809). 3-Methylxanthine can be used in studies related to ovarian cancer and neurotoxic convulsions .
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Cyclic GMP sodium (Standard)
Cyclic GMP sodium (Standard)
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Cat. No.: HY-113469AR
CAS No.: 40732-48-7
Category:  

Natural Products Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Cyclic GMP sodium (Standard) is the analytical standard of Cyclic GMP sodium (HY-113469A). This product is intended for research and analytical applications. Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .
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Phensuximide (Standard)
Phensuximide (Standard)
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Cat. No.: HY-B1730R
CAS No.: 86-34-0
Target:  

Cyclic GMP-AMP Synthase Reference Standards

Research Areas:  

Neurological Disease Metabolic Disease

Phensuximide (Standard) is the analytical standard of Phensuximide. This product is intended for research and analytical applications. Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal .
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Kaurenoic acid (Standard)
Kaurenoic acid (Standard)
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Cat. No.: HY-N1469R
CAS No.: 6730-83-2
Category:  

other families Terpenoids Diterpenoids Senna siamea (Lamarck) H. S. Irwin & Barneby Plants Compositae

Target:  

Reference Standards Potassium Channel

Kaurenoic acid (Standard) is the analytical standard of Kaurenoic acid. This product is intended for research and analytical applications. Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO–cyclic GMP–PKG–ATP-sensitive potassium channel signaling pathway .
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SDZ-MKS 492 (Standard)
SDZ-MKS 492 (Standard)
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Cat. No.: HY-100164R
CAS No.: 114606-56-3
Synonyms: MKS 492 (Standard)
Target:  

Phosphodiesterase (PDE) Reference Standards

Research Areas:  

Inflammation/Immunology

SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492 (HY-100164). This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats .
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