114606-56-3
114606-56-3
Chemical Structure
SDZ-MKS 492
Synonym(s): MKS 492
- CAS. Nr.: 114606-56-3
- Formula:C20H27N5O6
- Molecular Weight:433.46
IUPAC Name: (R)-8-((1-(3,4-dimethoxyphenyl)-2-hydroxyethyl)amino)-7-(2-methoxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: VZLFAVFWNOZVFM-ZDUSSCGKSA-N
SMILES: O=C(N1C)N(C)C2=C(N(CCOC)C(N[C@H](C3=CC=C(OC)C(OC)=C3)CO)=N2)C1=O
Biological Activity: SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats[1].
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SDZ-MKS 492 | 99.77% | SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats. | ||||||||||||||||||||
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SDZ-MKS 492 (Standard) | ≥98% | SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492 (HY-100164). This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats. | ||||||||||||||||||||
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