6730-83-2
6730-83-2
Chemical Structure
Kaurenoic acid
- CAS No.: 6730-83-2
- Formula:C20H30O2
- Molecular Weight:302.45
IUPAC Name: (4R,4aS,6aS,9R,11aR,11bS)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid
InChIKey: NIKHGUQULKYIGE-OTCXFQBHSA-N
SMILES: C[C@@]1(C(O)=O)CCC[C@@]2(C)[C@@]3([H])[C@@]4(CC([C@H](CC3)C4)=C)CC[C@]12[H]
Biological Activity: Kaurenoic acid is a diterpene derived from Sphagneticola trilobata. Kaurenoic acid has antibacterial, anti-inflammatory, anticonvulsant, analgesic, and aortic vasodilating effects[1][2][3][4].
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Kaurenoic acid | 99.93% | Kaurenoic acid is a diterpene derived from Sphagneticola trilobata. Kaurenoic acid has antibacterial, anti-inflammatory, anticonvulsant, analgesic, and aortic vasodilating effects. | ||||||||||||||||||||
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Kaurenoic acid (Standard) | ≥98% | Kaurenoic acid (Standard) is the analytical standard of Kaurenoic acid. This product is intended for research and analytical applications. Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO–cyclic GMP–PKG–ATP-sensitive potassium channel signaling pathway. | ||||||||||||||||||||
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References
- [1]. Carlos R Tirapelli, et al. Analysis of the mechanisms underlying the vasorelaxant action of kaurenoic acid in the isolated rat aorta. Eur J Pharmacol. 2004 May 25;492(2-3):233-41. [Content Brief]
- [2]. Sergio M Borghi, et al. The diterpene from Sphagneticola trilobata (L.) Pruski, kaurenoic acid, reduces lipopolysaccharide-induced peritonitis and pain in mice. J Ethnopharmacol. 2021 Jun 12:273:113980. [Content Brief]
- [3]. Theophine C Okoye, et al. Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis. Pharmacol Biochem Behav. 2013 Aug:109:38-43. [Content Brief]
- [4]. Mizokami SS, et al. Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. J Nat Prod. 2012 May 25;75(5):896-904. [Content Brief]
