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Cat. No.: HY-N3972

Grandifloric acid

Grandifloric acid is a Diterpenoids product that can be isolated from the herbs of Siegesbeckia orientalis L..

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CAS No.: 22338-69-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Grandifloric acid is a Diterpenoids product that can be isolated from the herbs of Siegesbeckia orientalis L.^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>100 μM Compound: 27	Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 20116261]
RAW264.7	IC₅₀	>25 μM Compound: 27	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide release pretreated for 15 mins before LPS challenge measured after 24 hrs by Griess method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide release pretreated for 15 mins before LPS challenge measured after 24 hrs by Griess method	[PMID: 21334121]
RAW264.7	IC₅₀	25.4 μM Compound: 20	Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by Griess reagent based assay Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by Griess reagent based assay	[PMID: 33476145]

CAS No. 22338-69-8
Molecular Weight 318.45
Formula C₂₀H₃₀O₃
SMILES

O[C@@H]1[C@]2(C3)[C@](CC[C@@]3([H])C1=C)([H])[C@]4([C@]([C@@](C)(CCC4)C(O)=O)([H])CC2)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.