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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
174 Results for "
Cysteine protease
" in MedChemExpress (MCE) Product Catalog:
Products (174)
174 Results for "Cysteine protease" in MCE Product Catalog:
90
90 Publications Verification
Synonyms: E64d; E64c ethyl ester
Research Areas:
Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Aloxistatin (E64d) exhibits entry-blocking effect for MERS-CoV.
64
64 Cited Publications
Cat. No.: HY-18234A
CAS No.: 103476-89-7
44
Category:
Target:
23
23 Cited Publications
Synonyms: Proteinase inhibitor E 64
Research Areas:
E-64 (Proteinase inhibitor E 64) is a potent irreversible inhibitor against general cysteine proteases with IC50 of 9 nM for papain.
19
Target:
Research Areas:
MDL-28170 (Calpain Inhibitor III) is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration . MDL-28170 also block γ-secretase .
17
Category:
Carica papaya L. Natural Products Caricaceae Plants Disease Research Fields Inflammation/Immunology
Target:
13
13 Cited Publications
Cat. No.: HY-18964
CAS No.: 110044-82-1
Synonyms: Calpain inhibitor I; Ac-LLnL-CHO; ALLN
Target:
Research Areas:
MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer .
8
8 Cited Publications
RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor .
8
7
7 Cited Publications
Cat. No.: HY-P81232
Synonyms: caspase-1 isoform alpha subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related Cysteine peptidase; Caspase 1 apoptosis related Cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.
6
6 Cited Publications
Cat. No.: HY-P701341
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CASP3; Protein Yama; Caspase 3; Caspase-3; Apopain; CASP-3; CPP32; CPP-32; CPP32B; SCA-1; Caspase 3, Apoptosis-Related Cysteine Peptidase; Yama; Caspase 3, Apoptosis-Related Cysteine protease; PARP Cleavage protease; SREBP Cleavage Activity 1; Procaspase3
5
4
4 Cited Publications
Cat. No.: HY-100227
CAS No.: 76684-89-4
Research Areas:
E 64c is a derivative of naturally occurring epoxide inhibitor of cysteine proteases, a Calcium-activated neutral protease (CANP) inhibitor and a very weak irreversible cathepsin C inhibitor. E 64c exhibits entry-blocking effect for MERS-CoV.
4
4 Cited Publications
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CL pro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CL pro, respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19. PF-00835231 can inhibit cell infections and also suppress infections in animal models .
3
3 Cited Publications
Research Areas:
K777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively .
3
3 Cited Publications
Research Areas:
LHVS is a potent, non-selective, irreversible, cell-permeable cysteine protease and cathepsin inhibitor. LHVS decreases actin ring formation. LHVS inhibits T. gondii invasion with an IC50 of 10 μM .
3
3 Cited Publications
Cat. No.: HY-17541
CAS No.: 921625-62-9
Cysteine Protease inhibitor is a cysteine protease inhibitor. Cysteine Protease inhibitor can be used in immunoblotting experiments of cells or tissues .
3
3 Cited Publications
Cat. No.: HY-17541A
CAS No.: 2197053-49-7
Target:
Research Areas:
Cysteine Protease inhibitor hydrochloride, an inhibitor of Cysteine Protease, binds to acetylcholinesterase (AChE). Cysteine Protease inhibitor hydrochloride is applicable to the research of Alzheimer's disease .
3
3 Cited Publications
Synonyms: N-Dodecylimidazole
3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
