110044-82-1
Chemical Structure
MG-101
Synonym(s): Calpain inhibitor I; Ac-LLnL-CHO; ALLN
- CAS No.: 110044-82-1
- Formula:C20H37N3O4
- Molecular Weight:383.53
IUPAC Name: (S)-2-acetamido-4-methyl-N-((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)pentanamide
InChIKey: FMYKJLXRRQTBOR-BZSNNMDCSA-N
SMILES: O=C(N[C@H](C=O)CCCC)[C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C
Biological Activity: MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1].
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MG-101 | 98.0% | MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer. | ||||||||||||||||||||
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MG-101 (GMP) | MG-101 (GMP) (Calpain inhibitor I (GMP)) is MG-101 (HY-18964) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer. | |||||||||||||||||||||
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Keywords