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D-Threitol (Standard)

" in MedChemExpress (MCE) Product Catalog:
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D-Threitol (Standard)
D-Threitol (Standard)
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Cat. No.: HY-W012846R
CAS No.: 2418-52-2
Category:  

Microorganisms Disease markers Endocrine diseases Endogenous metabolite Saccharides

Target:  

Reference Standards Endogenous Metabolite Glycosidase

D-Threitol (Standard) is the analytical standard of D-Threitol (HY-W012846). This product is intended for research and analytical applications. D-Threitol is a naturally occurring four-carbon sugar alcohol and an α-glucosidase (α‑glucosidase) inhibitor with an IC50 of 49 mM against yeast α-glucosidase, and it is orally active. D-Threitol modulates gut microbiota composition, increases microbial diversity, enriches beneficial bacterial genera, and restores fecal short-chain fatty acid levels. D-Threitol reduces body weight gain and fat accumulation, improves glucose tolerance and insulin sensitivity, and alleviates liver, kidney, and pancreatic tissue damage. D-Threitol inhibits hepatic accumulation of ceramides and diacylglycerols. D-Threitol preserves glomerular morphology and islet structure in diabetes models. D-Threitol is also a low-calorie sweetener. D-Threitol serves as a cryoprotective polyol that stabilizes protein structure at low temperatures. D-Threitol is used in research on type 2 diabetes and as an antifreeze agent for the Alaskan beetle .
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