1 Result for "

DNA-PK-IN-16

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DNA-PK-IN-16" in MCE Product Catalog:

Cat. No.: HY-181848
Target:  

DNA-PK Apoptosis

Research Areas:  

Cancer

DNA-PK-IN-16 is an orally active DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 10.2 nM. DNA-PK-IN-16 induces the upregulation of γH2A.X, a biomarker of DNA double-strand breaks. DNA-PK-IN-16 exhibits antiproliferative activity in various cancer cell lines. DNA-PK-IN-16 enhances the infiltration of CD8 + T cells in tumor tissues through synergistic action with anti-PD-L1 monoclonal antibody. DNA-PK-IN-16 is applicable for cancer research .
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