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Dihydroberberine (Standard)

" in MedChemExpress (MCE) Product Catalog:
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Dihydroberberine (Standard)
Dihydroberberine (Standard)
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Cat. No.: HY-N1934R
CAS No.: 483-15-8
Category:  

Alkaloids other families Plants Isoquinoline Alkaloids

Target:  

Reference Standards Potassium Channel HSP

Dihydroberberine (Standard) is the analytical standard of Dihydroberberine. This product is intended for research and analytical applications. Dihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene (hERG) channel and significantly reduces the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-κB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy .
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