2 Results for "

Dolutegravir (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Dolutegravir (Standard)" in MCE Product Catalog:

Cat. No.: HY-13238R
CAS No.: 1051375-16-6
Synonyms: S/GSK1349572 (Standard)
Research Areas:  

Infection

Dolutegravir (Standard) is the analytical standard of Dolutegravir. This product is intended for research and analytical applications. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM) .
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Cat. No.: HY-100083R
CAS No.: 1335210-23-5
Target:  

Reference Standards HIV

Research Areas:  

Others

Dolutegravir intermediate-1 (Standard) is the analytical standard of Dolutegravir intermediate-1 (HY-100083). This product is intended for research and analytical applications. Dolutegravir intermediate-1 is a synthetic intermediate of Dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
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