33 Results for "

Domain III

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "Domain III" in MCE Product Catalog:

12
12 Publications Verification
製品番号: HY-P70664
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Fibronectin type III Domain-containing protein 5; Fibronectin type III repeat-containing protein 2; Irisin; FNDC5
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4
4 Cited Publications
製品番号: HY-P72534
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Fibronectin type III Domain-containing protein 5; Irisin; FNDC5; FRCP2
Species:  
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3
3 Cited Publications
製品番号: HY-P70665
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Fibronectin type III Domain-containing protein 5; Fibronectin type III repeat-containing protein 2; Irisin; FNDC5
Species:  
Source:  
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1
1 Cited Publications
製品番号: HY-P76129
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E/Envelope protein (Domain III, His)
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製品番号: HY-P99155
CAS 番号: 667901-13-5
別名: 2F8; HUMAX-EGFR

Target:  

EGFR

研究分野:  

Cancer

Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer .
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製品番号: HY-138053
CAS 番号: 90831-71-3
別名: Ristomycin III
Target:  

Antibiotic

研究分野:  

Cardiovascular Disease Infection

Ristocetin A sulfate (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor (VWF) and bacterial cell wall components. Ristocetin A sulfate interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation, Ristocetin A sulfate drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A sulfate not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A sulfate is widely used in studies related to thromboembolic diseases and bacterial infections .
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製品番号: HY-NP131
Recombinant Humanized Type III Collagen 10.4kDa is a novel biomaterial that have anticancer effects. Recombinant Humanized Type III Collagen 10.4kDa activates discoidin domain receptor 1 (DDR1), and thus inhibits autophagy, proliferation, and migration of cancer cells, and induces apoptosis .
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製品番号: HY-124427
CAS 番号: 83415-79-6
Lithospermidin B is a derivative of Shikonin (HY-N0822) and an inhibitor of SARS-CoV-2 main protease (M pro). Lithospermidin B can be used for the research of COVID-19 .
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製品番号: HY-148366
純度:  98.99%
研究分野:  

Cancer

NecroIr2 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr2 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr2 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL), and regulates CDK4 expression .
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製品番号: HY-P99155A
CAS 番号: 667901-13-5

Target:  

EGFR

研究分野:  

Cancer

Zalutumumab (powder) is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab (powder) binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab (powder) binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab (powder) can be used for the research of cancer .
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製品番号: HY-P991779

Target:  

EGFR

研究分野:  

Cancer

Anti-Mouse/Human/Canine HER2 (domain III) Antibody (H2Mab-19) reacts with domain III of human and canine HER2. Anti-Mouse/Human/Canine HER2 (domain III) Antibody (H2Mab-19) exerts antitumor activity in mouse oral cancer xenografts. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .
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製品番号: HY-P99306
CAS 番号: 1310460-86-6
別名: DS 1024; Zatuximab

Target:  

EGFR

研究分野:  

Cancer

Modotuximab (DS 1024) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab binds non-overlapping epitopes on domain III of EGFR, a domain that is intact in EGFRvIII. Modotuximab has antitumor activity in vivo .
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製品番号: HY-P1816
CAS 番号: 136466-51-8
Target:  

Integrin

研究分野:  

Cancer

The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .
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製品番号: HY-150683
CAS 番号: 3031654-46-0
研究分野:  

Cancer

NC-III-49-1 is a potent bivalent bromodomain and extraterminal domain (BET) inhibitor. NC-III-49-1 shows binding potential for BRD4-1, BRD4-2, BRD4-T, BRDT-1, BRDT-2, BRDT-T with Kd values of 0.095, 0.32, 0.29, 0.089, 5.5, 0.058 nM, respectively. NC-III-49-1 shows antiproliferative activity. NC-III-49-1 decreases the expression of c-Myc .
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製品番号: HY-E70834
Target:  

JAK

研究分野:  

Cancer

JAK1 is a non-receptor tyrosine kinase that plays a critical role in cell signaling via type I/II cytokines and interferons (IFNs). JAK1(JH1) is a kinase domain. JAK1(JH1) Recombinant Human Active Protein Kinase is a recombinant JAK1(JH1) protein that can be used to study JAK1(JH1)-related functions .
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製品番号: HY-P991784

Target:  

EGFR

研究分野:  

Others

Anti-Mouse/Human EGFR (domain III) Antibody (EMab-88) reacts with domain III of the mouse and human EGFR. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
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製品番号: HY-P73535
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III, His)
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製品番号: HY-NP185
Chicken Tenascin,suitable for cell culture is a glycoprotein that forms disulfide-linked hexamers. Chicken Tenascin,suitable for cell culture is composed of repetitive domains, including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Chicken Tenascin,suitable for cell culture can be used for cell culture .
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製品番号: HY-P87519
別名: FRCP2, FNDC5, Fibronectin type III Domain-containing protein 5, Fibronectin type III repeat-containing protein 2

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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製品番号: HY-P76935
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Fibronectin type III Domain-containing protein 4; Fibronectin type III repeat-containing protein 1; FRCP1
Species:  
Source:  
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