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Results for "

ENO1

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

2

Inhibitory Antibodies

1

Natural
Products

4

Recombinant Proteins

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131904
    POMHEX
    3 Publications Verification

    		 Enolase Apoptosis Metabolic Disease Cancer
    POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor [1].
    POMHEX
  • HY-117778
    SF2312

    		Enolase Bacterial Antibiotic Infection Cancer
    SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions [1].
    SF2312
  • HY-131904A
    Hex

    		Enolase Parasite Infection Cancer
    Hex is an enolase inhibitor and antimalarial agent with Ki values of 74.4 nM and 269.4 nM for ENO2 and ENO1, respectively. Hex is a NfENO and TbENO inhibitor with IC50s value of 0.14 μM and 2.1 μM, respectively. Hex has antimalarial activity against Plasmodium falciparum 3D7, Naegleria fowleri trophozoites and Plasmodium berghei ANKA strain. Hex has anti-tumor effects against intracranial tumors [1] .
    Hex
  • HY-108868
    Mersalyl

    Salirgan; Salurin; Salyrgan

    		 HIF/HIF Prolyl-Hydroxylase VEGFR Metabolic Disease
    Mersalyl (Salirgan) is a potent vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1) inducer. Mersalyl induces VEGF and ENO1 mRNA expression. Mersalyl shows diuresis effects [1] .
    Mersalyl
  • HY-RS16574
    Eno1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Eno1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eno1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eno1 Mouse Pre-designed siRNA Set A
    Eno1 Mouse Pre-designed siRNA Set A
  • HY-102062A
    Nω-Propyl-L-arginine hydrochloride
    1 Publications Verification

    N-omega-Propyl-L-arginine hydrochloride

    		 NO Synthase Neurological Disease
    Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS) .
    Nω-Propyl-L-arginine hydrochloride
  • HY-102062
    Nω-Propyl-L-arginine
    1 Publications Verification

    N-omega-Propyl-L-arginine

    		 NO Synthase Neurological Disease
    Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS) .
    Nω-Propyl-L-arginine
  • HY-117778B
    SF2312 ammonium

    		Enolase Bacterial Antibiotic ATP Synthase Infection Cancer
    SF2312 ammonium is a phosphonate Antibiotic and Enolase inhibitor, with an IC50 of 18.4 nM against E. coli enolase. SF2312 ammonium reduces intracellular ATP levels and inhibits glycolytic flux. SF2312 ammonium exhibits activity against both Gram-positive and Gram-negative bacteria, and exerts synergistic effects against E. coli when combined with Fosfomycin (HY-B1075A). SF2312 ammonium shows selective toxicity toward gliomas with ENO1 gene knockout. SF2312 ammonium can be used in research related to bacterial infections and gliomas [1] .
    SF2312 ammonium
  • HY-179578
    SU212

    		Enolase AMPK Autophagy Apoptosis mTOR Caspase Metabolic Disease Cancer
    SU212 is a podophyllotoxin-derived ENO1 inhibitor and AMPK activator. SU212 can selectively induce oxidative phosphorylation, reduce glycolysis activity and glucose uptake in tumor cells, and directly bind to ENO1 without affecting these pathways in normal cells. SU212 induces apoptosis and promotes ENO1 degradation via proteasomal and autophagic pathways without inhibiting the catalytic activity. SU212 leads to mitotic arrest and apoptosis in TNBC (triple-negative breast cancer) cells by activating AMPK, demonstrating potent anti-tumor activity in vitro. SU212 inhibits tumor growth and metastasis in syngeneic, xenograft, and diabetic mouse models, exhibiting an excellent safety profile. SU212 can be used in research on t TNBC, diabetes, and fatty liver disease [1] .
    SU212
  • HY-RS04378
    ENO1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ENO1 Human Pre-designed siRNA Set A contains three designed siRNAs for ENO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ENO1 Human Pre-designed siRNA Set A
    ENO1 Human Pre-designed siRNA Set A
  • HY-RS23007
    Eno1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Eno1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eno1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eno1 Rat Pre-designed siRNA Set A
    Eno1 Rat Pre-designed siRNA Set A
  • HY-P991972
    Anti-ENO1 Antibody

    		Enolase Cancer
    Anti-ENO1 Antibody is an anti-ENO1 antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-ENO1 Antibody
  • HY-P991973
    HuL001

    		Enolase Cancer
    HuL001 is a specific monoclonal antibody targeting ENO1. HuL001 remodels the tumor microenvironment by inhibiting cancer-associated fibroblasts, thereby suppressing the progression of multiple myeloma. HuL001 can be used for research on cancers such as colorectal cancer, pancreatic ductal adenocarcinoma, and myeloma [1].
    HuL001
  • HY-162168
    Anti-inflammatory agent 71

    		COX Inflammation/Immunology
    Anti-inflammatory agent 71 (Compound 3.2) is an anti-inflammatory agent that can reduce the levels of neutrophils, COX-2, nitrotyrosine, IL-1b, and C-reactive protein, while increasing the level of eNOS .
    Anti-inflammatory agent 71
  • HY-102062R
    Nω-Propyl-L-arginine (Standard)

    N-omega-Propyl-L-arginine (Standard)

    		 Reference Standards NO Synthase Neurological Disease
    Nω-Propyl-L-arginine (Standard) is the analytical standard of Nω-Propyl-L-arginine (HY-102062). This product is intended for research and analytical applications. Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS) .
    Nω-Propyl-L-arginine (Standard)

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