2321366-46-3
2321366-46-3
Chemical Structure
Nω-Propyl-L-arginine hydrochloride
Synonym(s): N-omega-Propyl-L-arginine hydrochloride
- CAS No.: 2321366-46-3
- Formula:C9H21ClN4O2
- Molecular Weight:252.74
IUPAC Name: Nw-propyl-L-arginine hydrochloride
InChIKey: YTPXYHYMXLUNPN-FJXQXJEOSA-N
SMILES: N[C@@H](CCCNC(NCCC)=N)C(O)=O.[H]Cl
Biological Activity: Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nω-Propyl-L-arginine hydrochloride | 99.88% | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-130658D-NMMA acetate -
Similarity Score 0.80
HY-18732ARL-NMMA acetate (Standard) -
Similarity Score 0.79
HY-113216BAsymmetric dimethylarginine dihydrochloride -
Similarity Score 0.78
HY-115411L-Hydroxy arginine acetate -
Similarity Score 0.78
HY-W698343NG-Hydroxy-L-arginine acetate -
Similarity Score 0.77
HY-172764L-ENIPO hydrochloride -
Similarity Score 0.74
HY-U00432BS-MTC acetate -
Similarity Score 0.73
![N6-[(Allylamino]carbonothioyl]lysine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub> Chemical Structure](//file.medchemexpress.com/product_pic/hy-w748540.gif)
HY-W748540N6-[(Allylamino]carbonothioyl]lysine-13C6,15N2 -
Similarity Score 0.73
HY-115389Argimesna ethanesulfonate -
Explore the MedChemAI to find more analogs
![N6-[(Allylamino]carbonothioyl]lysine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub> Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w748540.gif)
References
- [1]. Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40(24):3869-70. [Content Brief]
- [2]. Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503(1-3):103-7. [Content Brief]
