3 Results for "

Epipodophyllotoxin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Epipodophyllotoxin" in MCE Product Catalog:

Cat. No.: HY-N7654
CAS No.: 4375-07-9
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro .
loading...
    loading...
Cat. No.: HY-N2812
CAS No.: 1180-35-4
Synonyms: 4-O-Epipodophyllotoxinyl acetate
Target:  

HSV VSV

Epipodophyllotoxin acetate (4-O-Epipodophyllotoxinyl acetate; compound 4) is a cyclolignan that exhibits antineoplastic and antiviral activities. Epipodophyllotoxin acetate inhibits HSV and VSV, with IC50s of 0.2 and 0.1 μg/mL, respectively .
loading...
    loading...
Cat. No.: HY-106122
CAS No.: 105655-99-0
Synonyms: VP 19
Research Areas:  

Cancer

NK-611 (VP 19) is an epipodophyllotoxin derivative. NK-611 induces DNA double-strand breaks by inhibiting topoisomerase II (IC50 = 56 μM). NK-611 does not inhibit microtubule polymerization, thus avoiding the side effects of the parent compound, Podofilox (HY-15552). NK-611 exhibits broad-spectrum antitumor activity and demonstrates potent efficacy in in vivo models of leukemia. NK-611 can be used in cancer research .
loading...
    loading...