4375-07-9
Chemical Structure
(-)-Epipodophyllotoxin
- CAS No.: 4375-07-9
- Formula:C22H22O8
- Molecular Weight:414.41
IUPAC Name: (5R,5aR,8aR,9S)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
InChIKey: YJGVMLPVUAXIQN-LGWHJFRWSA-N
SMILES: O=C1[C@]([C@]2([H])CO1)([H])[C@@](C(C=C3OC)=CC(OC)=C3OC)([H])C4=CC(OCO5)=C5C=C4[C@H]2O
Biological Activity: (-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(-)-Epipodophyllotoxin | 99.95% | (-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro. | ||||||||||||||||||||
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Similarity Score 1.00
HY-15494Picropodophyllin -
Similarity Score 1.00
HY-15552Podofilox -
Similarity Score 1.00
HY-N9275Isopicropodophyllin -
Similarity Score 0.90
HY-174354'-Demethylepipodophyllotoxin -
Similarity Score 0.90
HY-N23234'-Demethylpodophyllotoxin -
Similarity Score 0.89
HY-15494SPicropodophyllin-d3 -
Similarity Score 0.83
HY-N2812Epipodophyllotoxin acetate -
Similarity Score 0.78
HY-N2500Deoxypodophyllotoxin -
Similarity Score 0.78
HY-N8038Isoanthricin -
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