1. Apoptosis
  2. Apoptosis
  3. (-)-Epipodophyllotoxin

(-)-Epipodophyllotoxin 

Cat. No.: HY-N7654
Handling Instructions

(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro.

For research use only. We do not sell to patients.

(-)-Epipodophyllotoxin Chemical Structure

(-)-Epipodophyllotoxin Chemical Structure

CAS No. : 4375-07-9

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Description

(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro[1].

Molecular Weight

414.41

Formula

C₂₂H₂₂O₈

CAS No.

4375-07-9

SMILES

O=C1[[email protected]]([[email protected]]2([H])CO1)([H])[[email protected]@](C(C=C3OC)=CC(OC)=C3OC)([H])C4=CC(OCO5)=C5C=C4[[email protected]]2O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(-)-EpipodophyllotoxinApoptosisantiproliferativecancerAmericanmayapplePodophyllum peltatummitoticspindleassemblyInhibitorinhibitorinhibit

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(-)-Epipodophyllotoxin
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