1 Result for "

G 3130

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "G 3130" in MCE Product Catalog:

Cat. No.: HY-111300
CAS No.: 848952-37-4
Target:  

HSP EGFR

Research Areas:  

Cancer

G3130 is a reversible HSP90 inhibitor with a Kd value of 280 nM for the N-terminal ATP-binding domain of purified human Hsp90α. G3130 binds to the adenine site via a multi-hydrogen bond network . G3130 induces the degradation of Hsp90 client protein Her-2 in breast cancer cells. G3130 activates Hsp70 promoter-driven luciferase expression in 293T cells. G3130 can be used in breast cancer-related research .
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