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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
GSPT1 degrader-5
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "GSPT1 degrader-5" in MCE Product Catalog:
Cat. No.: HY-162534
CAS No.: 3034764-38-7
Research Areas:
GSPT1 degrader-5 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 20 nM. GSPT1 degrader-5 induces GSPT1 protein degradation via the ubiquitin-proteasome pathway. GSPT1 degrader-5 can be used in breast cancer-related research [1].
Cat. No.: HY-175040
Research Areas:
PROTAC FLT-3 degrader 5 is an orally active FLT3 PROTAC degrader with a DC50 of 1.2 nM. PROTAC FLT-3 degrader 5 also acts as a molecular glue to degrade GSPT1 and IKZF1/3, with DC50 values of 8.54 nM, 0.02 nM and 0.79 nM, respectively. PROTAC FLT-3 degrader 5 mediates the degradation of FLT3, GSPT1 and IKZF1/3 through interaction with the cereblon E3 ubiquitin ligase complex. PROTAC FLT-3 degrader 5 can be used in the research of acute myeloid leukemia [1].
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
