6 Results for "

Gamma-Mangostin

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Gamma-Mangostin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N1957
CAS No.: 31271-07-5
Synonyms: γ-Mangostin
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
loading...
    loading...
25
25 Publications Verification
Cat. No.: HY-P1731C
Synonyms: LY3298176 sodium
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide sodium exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide sodium can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
loading...
    loading...
Cat. No.: HY-N1957R
CAS No.: 31271-07-5
Synonyms: γ-Mangostin (Standard)
Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
loading...
    loading...
Cat. No.: HY-P1731CP
CAS No.: 2023788-19-2
Tirzepatide (LY3298176) (crude) is the crude form of Tirzepatide (HY-P1731).Tirzepatide (LY3298176) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
loading...
    loading...
Cat. No.: HY-186194
CAS No.: 18356-05-3
Target:  

Drug Derivative

Research Areas:  

Infection

6-Methoxy-γ-mangostin is a synthetic analogue of prenylated xanthone. 6-Methoxy-γ-mangostin can be used for research on bacterial infection .
loading...
    loading...
Cat. No.: HY-P4376B
Target:  

CaSR

Research Areas:  

Others

Gamma-Glu-Abu acetate is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu acetate interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group .
loading...
    loading...