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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Ganglioside GM 3
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Ganglioside GM 3" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia .
Cat. No.: HY-114456AS
CAS No.: 2260669-91-6
Cat. No.: HY-165160
CAS No.: 69345-49-9
Synonyms: GM3-Neugc ammonium; NeuGc-GM3 ammonium
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Research Areas:
N-Glycolyl-ganglioside GM3 ammonium is a biochemical reagent.
Cat. No.: HY-114456S
Cat. No.: HY-152002S
CAS No.: 2692623-85-9
Cat. No.: HY-165665S
Cat. No.: HY-W127324
CAS No.: 1046791-63-2
Synonyms: NeuAcα(2-3)Galβ(1-4)Glc-ceramide (phyto-type)
Cat. No.: HY-173643
Synonyms: Biotin-C6:0-GM3 ammonium; N-Hexanoyl-biotin-monosialoGanglioside GM3 ammonium
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Research Areas:
C6 Biotin ganglioside gm3 (d18:1/6:0) (Biotin-C6:0-gm3) ammonium is a derivative of ganglioside GM3. C6 Biotin ganglioside gm3 (d18:1/6:0) ammonium can be used to detect or immobilize ganglioside GM3 through interaction with the biotin ligand .
Cat. No.: HY-171443
CAS No.: 94458-63-6
Synonyms: Lyso-GM3
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Research Areas:
Lyso-Monosialoganglioside GM3 (Lyso-GM3) is an analogue of Ganglioside GM3 (HY-114456) with antitumor activities. Lyso-Monosialoganglioside inhibits EGF-induced increases in EGFR kinase activity in A431 epithelial cancer cells .
Cat. No.: HY-W342441
CAS No.: 54827-14-4
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Research Areas:
Monosialoganglioside GM3 (bovine) is a monosialoganglioside and an inhibitor of VEGFR2 and Akt. At a concentration of 20 μM, Monosialoganglioside GM3 inhibits angiogenesis and reduces the proliferation and migration of human umbilical vein endothelial cells (HUVECs) by inhibiting VEGFR2 and Akt phosphorylation. Ganglioside GM3 also inhibits ferroptosis, providing protective effects during the formation of abdominal aortic aneurysms. Additionally, Monosialoganglioside GM3 (bovine) acts as an inhibitor of insulin signaling, inducing the dissociation of the insulin receptor (IR)-Caveolin-1 complex from lipid microdomains and causing insulin resistance in adipocytes. Monosialoganglioside GM3 (bovine) can be used in cancer and metabolic disease research .
Cat. No.: HY-E70049
CAS No.: 67338-98-1
Synonyms: GM2/GD2 synthase
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Research Areas:
beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides .
Cat. No.: HY-N15906
CAS No.: 94458-61-4
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
