1 Result for "

HDACs/EZH2-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HDACs/EZH2-IN-1" in MCE Product Catalog:

Cat. No.: HY-169400
Research Areas:  

Cancer

HDACs/EZH2-IN-1 (Compound 22a) is a HDACs/EZH2 inhibitor (EZH2 Y641N inhibition rate at 50 nM: 98%), with selective inhibition against HDAC1 and HDAC6 (IC50: 0.23 μM and 0.07 μM, respectively). HDACs/EZH2-IN-1 exerts a antiproliferative effect on diffuse large B-cell lymphoma cells harboring an EZH2 mutation and on various acute myeloid leukemia cells. HDACs/EZH2-IN-1 has the ability to induce cell differentiation and Apoptosis .
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