5 Results for "

HPV16+E6

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "HPV16+E6" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P10428
Target:  

HPV

Research Areas:  

Infection

E6AP-mimicking peptide (compound 13) is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture .
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Cat. No.: HY-P89419

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, FC, IF-Tissue

Reactivity:  

Virus

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Cat. No.: HY-N20712
CAS No.: 59632-76-7
Anisomelic acid is a human papillomavirus HPV16 E6 and HPV E7 depletor . Anisomelic acid directly interacts with HPV16 E6, promotes its ubiquitination and proteasomal degradation by recruiting E3 ubiquitin ligase, downregulates E6 and facilitates E7 degradation. Anisomelic acid induces endogenous mitochondrial apoptosis, activates caspase-3, causes cleavage of PARP, and triggers p53-independent endogenous apoptosis by depleting cIAP2. Anisomelic acid can be used in research related to HPV-positive cancers and cervical cancer .
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Cat. No.: HY-P700914
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HLA-A; MHC Class 1 Antigen; Major Histocompatibility Complex, Class I, A; MHC ClassI Antigen; HLA Class I Histocompatibility Antigen, A Alpha Chain; Lymphocyte Antigen; MHC Class I Antigen HLA-A Heavy Chain; HLA-A*6602 Antigen; Leukocyte Antigen Class I-A
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700915
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HLA-A; MHC Class 1 Antigen; Major Histocompatibility Complex, Class I, A; MHC ClassI Antigen; HLA Class I Histocompatibility Antigen, A Alpha Chain; Lymphocyte Antigen; MHC Class I Antigen HLA-A Heavy Chain; HLA-A*6602 Antigen; Leukocyte Antigen Class I-A
Species:  
Human
Source:  
HEK293
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