1 Result for "

HSP90/mTOR-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HSP90/mTOR-IN-1" in MCE Product Catalog:

Cat. No.: HY-151137
CAS No.: 3033543-67-5
Target:  

mTOR HSP Apoptosis Autophagy

Research Areas:  

Cancer

HSP90/mTOR-IN-1 is a potent and orally active Hsp90 and mTOR inhibitor with IC50 values of 69 nM and 29 nM, respectively. HSP90/mTOR-IN-1 suppresses the proliferation of SW780 cells through the over-activation of the PI3K/AKT/mTOR pathway. HSP90/mTOR-IN-1 induces apoptosis and autophagy via selective Hsp90 and mTOR inhibition. HSP90/mTOR-IN-1 also has considerable in vivo anti-tumor activity. HSP90/mTOR-IN-1 can be used for researching bladder cancer [1].
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