1 Result for "

HY-P5912

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HY-P5912" in MCE Product Catalog:

Cat. No.: HY-P5912
Target:  

iGluR Calcium Channel

Research Areas:  

Neurological Disease

GluN1 (356-385) is a polypeptide targeting NMDAR GluN1. GluN1 (356-385) induces the production of autoantibodies, which reduce the density of cell surface NMDAR clusters, impair long-term potentiation, and decrease NMDAR-mediated Ca 2+ influx. As an immunogen, GluN1 (356-385) induces symptoms similar to anti-NMDAR encephalitis, including memory loss, in mice. GluN1 (356-385) can be used to establish a mouse model that mimics the pathogenesis of anti-NMDAR encephalitis. GluN1 (356-385) is applicable to research related to anti-NMDAR encephalitis .
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