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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
51 Results for "
Hydrazone
" in MedChemExpress (MCE) Product Catalog:
Products (51)
51 Results for "Hydrazone" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-16261B
CAS No.: 480998-12-7
Synonyms: (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)Hydrazone hydrochloride
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MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) hydrochloride is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN hydrochloride can be used to synthesize ADC .
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Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., β-thalassemia) .
1
1 Cited Publications
Cat. No.: HY-W077680
CAS No.: 1126-58-5
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Girard's P reagent is a reagent used in organic chemistry. Girard's P reagent is used to react with vanillin to form a hydrazone derivative, which is then combined with an ion selective electrode (ISE) to develop a potentiometric method for the determination of vanillin. Girard's P reagent can be used in the development of ion selective electrodes and in the study of organic analysis .
Cat. No.: HY-15932
CAS No.: 82692-93-1
Synonyms: TOOS sodium salt
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Cat. No.: HY-W074541
CAS No.: 123-46-6
Synonyms: Trimethylacetohydrazideammonium chloride
Cat. No.: HY-W010341
CAS No.: 1452-63-7
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2-Pyridinecarbohydrazide is a versatile heterocyclic building block widely used in medicinal chemistry and coordination chemistry, and it finds extensive applications in various synthetic fields. 2-Pyridinecarbohydrazide reacts with the reducing end of carbohydrates to enhance mass spectrometry ionization efficiency, enabling isomer-specific identification of monosaccharides, disaccharides, ketoses/aldoses, and quantitative mass spectrometry imaging of biological tissues .
Cat. No.: HY-16261A
CAS No.: 151038-96-9
Synonyms: (E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)Hydrazone
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Research Areas:
MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN can be used to synthesize ADC .
Cat. No.: HY-136131
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NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Cat. No.: HY-161752
CAS No.: 16371-55-4
Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system .
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Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors .
Cat. No.: HY-W009411
CAS No.: 33008-06-9
Cat. No.: HY-W012617
CAS No.: 553-53-7
Synonyms: Nicotinic acid hydrazide
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Nicotinohydrazide (Nicotinic acid hydrazide) is a precursor used for synthesizing hydrazone derivatives with antibacterial and antifungal activities. Nicotinohydrazide can be used in studies of bacterial and fungal infections .
Cat. No.: HY-W013677
CAS No.: 456-22-4
Cat. No.: HY-155907
CAS No.: 474922-26-4
Synonyms: DSPE-PEG5000-NH2 ammonium
Cat. No.: HY-136079
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Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cyanoacetohydrazide is a pharmaceutical intermediate. Cyanoacetohydrazide can be used to synthesize acylhydrazide hydrazone derivatives with antibacterial or anti-tumor activity .
Cat. No.: HY-117492
CAS No.: 13410-86-1
Synonyms: Isonicophen
Aconiazide (Isonicophen) is a orally active hydrazone derivative of isoniazid, and can be used for study of tuberculosis .
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Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells) .
Cat. No.: HY-172285
CAS No.: 871514-32-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
