33008-06-9
Chemical Structure
Dansyl hydrazine
- CAS No.: 33008-06-9
- Formula:C12H15N3O2S
- Molecular Weight:265.34
IUPAC Name: 5-(dimethylamino)naphthalene-1-sulfonohydrazide
InChIKey: KPQYDVAFRDWIBW-UHFFFAOYSA-N
SMILES: NNS(C1=CC=CC2=C(C=CC=C21)N(C)C)(=O)=O
Biological Activity: Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease[1][2][3].
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Dansyl hydrazine | 99.98% | Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease. | ||||||||||||||||||||
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Dansyl hydrazine-13C2 | Dansyl hydrazine-13C2 is the 13C-labeled Dansyl hydrazine (HY-W009411). Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease. | |||||||||||||||||||||
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References
- [1]. Sparkman DR, et al. Dansyl hydrazine labeling of polysaccharide bodies in human brain. Biotech Histochem. 1993;68(2):99-103. [Content Brief]
- [2]. Avigad G, et al. Dansyl hydrazine as a fluorimetric reagent for thin-layer chromatographic analysis of reducing sugars. J Chromatogr. 1977;139(2):343-347. [Content Brief]
- [3]. Ahamed AA, et al. A Julolidine Aldehyde Dansyl Hydrazine Schiff Base as Fluorescence Chemosensor for Zn2+ ions Recognition and its Application. J Fluoresc. 2025;35(6):4547-4557. [Content Brief]
