Dansyl chloride
Based on 1 Customer Validation
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 605-65-2
- Formula: C12H12ClNO2S
- Molecular Weight:269.75
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Storage:
4°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Dansyl chloride is used to provide fluorescent labeling for protein studies. Dansyl chloride reacts with α-chymotrypsin, making it a method for studying α-amino and other reactive groups in proteins and peptides. Dan sulfonyl chloride is very useful for determining the amino acid sequences of small peptides. Dansyl chloride's a typical aromatic sulfonyl chloride that can react with a variety of bases to form derivatives of varying stability. Some recommended steps for peptides include: (1) reagents, buffers, and labeling mixtures (2) labeling the peptides (3) hydrolysis (4) visualization of compounds on paper (5) analyzing the results[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 605-65-2
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Appearance Solid
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Molecular Weight 269.75
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Formula C12H12ClNO2S
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Color Light yellow to yellow
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SMILES
O=S(C1=C2C=CC=C(N(C)C)C2=CC=C1)(Cl)=O
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Synonyms
DNSCl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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