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Dansyl chloride  (Synonyms: DNSCl)

Cat. No.: HY-D0017 Purity: 99.97%
COA Handling Instructions

Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis.

For research use only. We do not sell to patients.

Dansyl chloride Chemical Structure

Dansyl chloride Chemical Structure

CAS No. : 605-65-2

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Based on 1 publication(s) in Google Scholar

Other Forms of Dansyl chloride:

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Description

Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis[1].

Molecular Weight

269.75

Formula

C12H12ClNO2S

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=S(C1=C2C=CC=C(N(C)C)C2=CC=C1)(Cl)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (46.34 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7071 mL 18.5357 mL 37.0714 mL
5 mM 0.7414 mL 3.7071 mL 7.4143 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.97%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7071 mL 18.5357 mL 37.0714 mL 92.6784 mL
5 mM 0.7414 mL 3.7071 mL 7.4143 mL 18.5357 mL
10 mM 0.3707 mL 1.8536 mL 3.7071 mL 9.2678 mL
15 mM 0.2471 mL 1.2357 mL 2.4714 mL 6.1786 mL
20 mM 0.1854 mL 0.9268 mL 1.8536 mL 4.6339 mL
25 mM 0.1483 mL 0.7414 mL 1.4829 mL 3.7071 mL
30 mM 0.1236 mL 0.6179 mL 1.2357 mL 3.0893 mL
40 mM 0.0927 mL 0.4634 mL 0.9268 mL 2.3170 mL
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Dansyl chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dansyl chloride
Cat. No.:
HY-D0017
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