871514-32-8
871514-32-8
Chemical Structure
Cy3 hydrazide
- CAS No.: 871514-32-8
- Formula:C31H40N4O7S2
- Molecular Weight:644.80
InChIKey: BNLBIEPQLXAGQW-UHFFFAOYSA-N
SMILES: O=C(CCCCC[N+]1=C(/C=C/C=C2N(CC)C3=CC=C(S(=O)(O)=O)C=C3C\2(C)C)C(C)(C)C4=C1C=CC(S(=O)([O-])=O)=C4)NN
Biological Activity: Cy3 hydrazide is a fluorescent probe for carbonylated proteins. Cy3 hydrazide covalently links to aldehyde or ketone residues on carbonylated proteins, reacts with protein carbonyl groups to form stable hydrazones, and enables fluorescent detection (Ex/Em = 555/570 nm)[1][2][3].
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Cy3 hydrazide | Cy3 hydrazide is a fluorescent probe for carbonylated proteins. Cy3 hydrazide covalently links to aldehyde or ketone residues on carbonylated proteins, reacts with protein carbonyl groups to form stable hydrazones, and enables fluorescent detection (Ex/Em = 555/570 nm). | |||||||||||||||||||||
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References
- [1]. Nina-Diogo A, et al. Synthesis of New Bodipy Hydrazide Fluorescent Probes for the Detection of Carbonylated Proteins Generated by Oxidative Stress. Chembiochem. 2024;25(19):e202400093. [Content Brief]
- [2]. Tamarit J, et al. Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. J Proteomics. 2012;75(12):3778-3788. [Content Brief]
- [3]. Pan D, et al. Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop. RNA. 2009;15(2):346-354. [Content Brief]
Keywords
