1452-63-7
Chemical Structure
2-Pyridinecarbohydrazide
- CAS No.: 1452-63-7
- Formula:C6H7N3O
- Molecular Weight:137.14
IUPAC Name: picolinohydrazide
InChIKey: BAQLNPIEFOYKNB-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CC=C1)NN
Biological Activity: 2-Pyridinecarbohydrazide is a versatile heterocyclic building block widely used in medicinal chemistry and coordination chemistry, and it finds extensive applications in various synthetic fields. 2-Pyridinecarbohydrazide reacts with the reducing end of carbohydrates to enhance mass spectrometry ionization efficiency, enabling isomer-specific identification of monosaccharides, disaccharides, ketoses/aldoses, and quantitative mass spectrometry imaging of biological tissues[1][2].
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2-Pyridinecarbohydrazide | 99.8% | 2-Pyridinecarbohydrazide is a versatile heterocyclic building block widely used in medicinal chemistry and coordination chemistry, and it finds extensive applications in various synthetic fields. 2-Pyridinecarbohydrazide reacts with the reducing end of carbohydrates to enhance mass spectrometry ionization efficiency, enabling isomer-specific identification of monosaccharides, disaccharides, ketoses/aldoses, and quantitative mass spectrometry imaging of biological tissues. | ||||||||||||||||||||
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- [1]. Surzhko V, et al. Synthesis of picolinohydrazides and their evaluation as ligands in the zinc-catalyzed hydrosilylation of ketones. Tetrahedron Letters. 2017 Mar 29;58(13):1343-1347.
- [2]. Wang L, et al. In-depth profiling of carbohydrate isomers in biological tissues by chemical derivatization-assisted mass spectrometry imaging. Anal Chim Acta. 2023;1278:341741. [Content Brief]
Keywords
