Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
78 Results for "
Immunogenic Peptide
" in MedChemExpress (MCE) Product Catalog:
Products (78)
78 Results for "Immunogenic Peptide" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P3719
CAS No.: 2022956-48-3
Target:
Research Areas:
Cat. No.: HY-165613
CAS No.: 656831-18-4
Synonyms: Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine
Research Areas:
Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection .
Cat. No.: HY-P3487
CAS No.: 1223335-84-9
Target:
Research Areas:
Cat. No.: HY-140692
Target:
Research Areas:
mPEG20000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
Cat. No.: HY-140693
Purity: ≥98.0%
Target:
Research Areas:
m-PEG30000-mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
Cat. No.: HY-140721
Target:
Research Areas:
Mal-PEG5000-mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
Cat. No.: HY-W1049092
Cat. No.: HY-P10862
Target:
IC50 values of 11.9, 12.5, 35.7, 206 and 136 nM, respectively. AH-D peptide reduces the viral load in the brain, suppresses inflammation, protects neurons, and does not damage the blood brain barrier. AH-D peptide restores antitumor immunity by decreasing circulating PD-L1 + exosomes, reducing intratumoral immunosuppressive cells (regulatory T cells, myeloid-derived suppressor cells), and enhancing T cell function. AH-D peptide inhibits membrane-enveloped viruses and cancer cell metastasis in vivo. AH-D peptide exhibits no immunogenicity and has negligible effects on normal tissues. AH-D peptide can be used for research in Zika virus and other mosquito-borne viruses, cancer immunotherapy and metastasis .
Cat. No.: HY-W012166
CAS No.: 42014-51-7
Synonyms: NHS-Bromoacetate
Target:
Research Areas:
N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .
Cat. No.: HY-P3488
CAS No.: 2032119-68-7
Target:
Research Areas:
Cat. No.: HY-140691
Purity: 99.89%
Target:
Research Areas:
mPEG10000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
Cat. No.: HY-140689
Purity: 97.27%
Target:
Research Areas:
m-PEG2000-mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
Cat. No.: HY-140719
Target:
Research Areas:
Mal-PEG2000-mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
Cat. No.: HY-P6355
CAS No.: 198274-43-0
Target:
Research Areas:
Cat. No.: HY-P3486
CAS No.: 199477-24-2
Target:
Research Areas:
Cat. No.: HY-P10701
CAS No.: 581799-39-5
Target:
Research Areas:
Cat. No.: HY-P11205A
Synonyms: Cys-txCD47 TFA
Research Areas:
Cat. No.: HY-P1610
CAS No.: 1018833-53-8
Target:
Research Areas:
Cat. No.: HY-174359C
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
