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Cat. No.: HY-P1610

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Asudemotide

Asudemotide (S-588410) is a peptide of human DEP domain-containing protein 1A. Asudemotide is an immunostimulant. Asudemotide has a sequence of H-Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile-OH. Asudemotide induces a tumor immune response in esophageal cancer. .

For research use only. We do not sell to patients.

CAS No.: 1018833-53-8
Formula: C₅₈H₈₀N₁₀O₁₇
Molecular Weight:1189.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Asudemotide Chemical Structure

CAS No.: 1018833-53-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1018833-53-8
Molecular Weight 1189.31
Formula C₅₈H₈₀N₁₀O₁₇
Sequence

Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile
Sequence Shortening

EYYELFVNI
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Dielectrophoresis (DEP)-Based Electrical Cell Sorting
Dielectrophoresis-based electrical cell sorting separates suspended cells by the motion generated when polarizable cells experience a non-uniform electric field; cell trajectory depends on cell size, medium conductivity, applied AC frequency, electric-field gradient, and cell dielectric properties, so cells with different DEP responses can be routed, trapped, levitated, or released without biochemical labeling. In practical DEP sorters, the readout is the spatial redistribution of cells into different outlets, traps, or recovered fractions; reported examples include DEP field-flow fractionation of leukocytes, breast cancer cells, CD34+ cells, and blood cells, continuous-flow hMSC/osteoblast sorting, and image-based single-cell recovery after DEP manipulation.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (256 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. H Daiko, et al.Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients. Cancer Immunol Immunother. 2020, 69, 11. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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