1 Result for "

Iptacopan TFA

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Iptacopan TFA" in MCE Product Catalog:

Cat. No.: HY-127105B
CAS No.: 1644670-38-1
Synonyms: LNP023 TFA
Iptacopan (LNP023) TFA is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan TFA exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan TFA can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G) .
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