1 Result for "

JAK/HDAC-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JAK/HDAC-IN-2" in MCE Product Catalog:

Cat. No.: HY-149283
CAS No.: 3029138-43-7
Target:  

JAK HDAC Apoptosis

Research Areas:  

Cancer

JAK/HDAC-IN-2 is a potent 2-amino-4-phenylaminopyrimidine JAK/HDAC dual-target inhibitor. JAK/HDAC-IN-2 potently inhibits HDAC3/6 and JAK1/2 at nanomolar levels. JAK/HDAC-IN-2 has proapoptotic activity and inhibits histone deacetylation and STAT3 phosphorylation. JAK/HDAC-IN-2 presents remarkable antiproliferative activity in both hematological malignancies and solid cancers .
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