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KRASG12C IN-20

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-182883
    KRASG12C IN-20

    		Ras Cancer
    KRASG12C IN-20 is an orally potent KRAS G12C inhibitor with an EC50 of 3.9 nM. KRASG12C IN-20 covalently modifies KRAS G12C in its inactive GDP-bound state and locks it to block oncogenic signal transduction. KRASG12C IN-20 exhibits significant activity in lung adenocarcinoma xenograft models. KRASG12C IN-20 can be used for research related to lung adenocarcinoma .
    KRASG12C IN-20

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