1 Result for "

KRASG12C-GDP

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRASG12C-GDP" in MCE Product Catalog:

Cat. No.: HY-182883
Target:  

Ras

Research Areas:  

Cancer

KRASG12C IN-20 is an orally potent KRAS G12C inhibitor with an EC50 of 3.9 nM. KRASG12C IN-20 covalently modifies KRAS G12C in its inactive GDP-bound state and locks it to block oncogenic signal transduction. KRASG12C IN-20 exhibits significant activity in lung adenocarcinoma xenograft models. KRASG12C IN-20 can be used for research related to lung adenocarcinoma .
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