1 Result for "

KWR 137

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KWR 137" in MCE Product Catalog:

Cat. No.: HY-168934
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

KWR137 is an orally active Werner protein (WRN) inhibitor with a human IC50 of 8 nM. KWR137 inhibits the ATPase activity required for WRN helicase function, induces WRN protein degradation, suppresses cancer cell proliferation, and slows tumor growth without causing weight loss or off-target effects. KWR137 can be used for the research of colorectal cancer .
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