1 Result for "

KWZY-11

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "KWZY-11" in MCE Product Catalog:

Cat. No.: HY-176713
CAS No.: 3077131-44-0
Research Areas:  

Cancer

KWZY-11 (Compound 11) is a potent PARP/CDK6 dual inhibitor with IC50 values of 156.8, 197.3, and 13.3 nM for PARP1, PARP2, and CDK6, respectively. KWZY-11 inhibits tumor cell proliferation by regulating the Wnt/β-catenin signaling pathway. KWZY-11 induces excessive DNA damage and apoptosis in MDA-MB-231 breast cancer cells .
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