1 Result for "

L444P GBA1 mutant fibroblasts

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "L444P GBA1 mutant fibroblasts" in MCE Product Catalog:

Cat. No.: HY-160426
CAS No.: 2270984-21-7
Target:  

Glycosidase

Research Areas:  

Neurological Disease

Gcase activator 3 is a β-glucocerebrosidase (GCase) activator with an EC50 of 1.49 μM. By binding to the allosteric site of GCase, Gcase activator 3 partially stabilizes GCase and enhances its activity. Gcase activator 3 can be conjugated with fluorophores to form fluorescent probes, which are used for high-throughput screening of GCase. Gcase activator 3 is applicable to research related to Gaucher's disease, Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy .
loading...
    loading...