2270984-21-7
2270984-21-7
Chemical Structure
Gcase activator 3
- CAS No.: 2270984-21-7
- Formula:C23H20N4O2
- Molecular Weight:384.43
InChIKey: JFOVNJQCUHRYOI-KRWDZBQOSA-N
SMILES: CN(C[C@@H]1OC2=CC=CC=C2OC1)C3=C4C=CC=CC4=NC(C5=CC=CN=C5)=N3
Biological Activity: Gcase activator 3 (compound 9Q) is a glucosidase (Glucosidase, GCase) activator that can partially stabilize GCase and increase its activity. Gcase activator 3 reduces mutant GCase protein misfolding and degradation in fibroblasts and dopaminergic midbrain neurons. Gcase activator 3 can be used in the study of Parkinson's disease (PD) and related synucleinopathies[1].
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Gcase activator 3 | 99.67% | Gcase activator 3 (compound 9Q) is a glucosidase (Glucosidase, GCase) activator that can partially stabilize GCase and increase its activity. Gcase activator 3 reduces mutant GCase protein misfolding and degradation in fibroblasts and dopaminergic midbrain neurons. Gcase activator 3 can be used in the study of Parkinson's disease (PD) and related synucleinopathies. | ||||||||||||||||||||
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References
Keywords
