1 Result for "

LT-1339-553

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LT-1339-553" in MCE Product Catalog:

Cat. No.: HY-184001
CAS No.: 3078683-57-2
LT-1339-553 is a selective, orally active RIPK1 inhibitor with IC50 values of 4.32, 95.74 and 84.33 nM against RIPK1, RIPK2 and RIPK3, respectively. LT-1339-553 exerts anti-necroptotic activity by inhibiting the AKT/PI3K/NF-κB pathway and the IL-17 pathway. LT-1339-553 reduces liver injury, inflammatory responses and collagen deposition. LT-1339-553 can be used in studies related to schistosomiasis-induced liver fibrosis .
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