1 Result for "

LY2624587

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "LY2624587" in MCE Product Catalog:

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Cat. No.: HY-P991656
CAS No.: 2125546-89-4

Target:  

CXCR Apoptosis p38 MAPK Akt

Research Areas:  

Cancer

LY-2624587 is a humanized IgG4 monoclonal antibody antagonist targeting CXCR4. LY-2624587 blocks SDF-1/CXCR4 interaction and SDF-1-induced GTP binding. LY-2624587 significantly inhibits cell migration and induces apoptosis in human lymphoma and leukemia cells. LY-2624587 also inhibits CXCR4 and SDF-1 mediated cell signaling including activation of MAPK and AKT. LY-2624587 can be used for human hematological malignancies like acute myeloid leukemia (AML) research .
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