1 Result for "

LY86057

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "LY86057" in MCE Product Catalog:

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Cat. No.: HY-123567
CAS No.: 148966-66-9
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

LY86057 is an ergoline derivative without N1 substituents. It has higher affinity for porcine, squirrel monkey and human 5-HT2 receptors than rats and is an antagonist of 5-HT2 receptors. When studying the differences in recognition of a series of ergolines between species, LY86057 was found to be more selective for 5-HT2 receptors. Compared with LY53857, LY108742 resulted in a higher affinity for rat 5-HT2 receptors even when the N1 substituent was only methyl.
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