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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
Lewis acid
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "Lewis acid" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
4
4 Cited Publications
Cat. No.: HY-P1408
CAS No.: 404882-00-4
2
2 Cited Publications
Cat. No.: HY-160109
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Research Areas:
Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
1
1 Cited Publications
Cat. No.: HY-W020014
CAS No.: 78-98-8
1
Category:
Polysaccharides Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
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1
1 Cited Publications
Research Areas:
Semustine is an orally active, blood-brain barrier permeable antitumor alkylating agent with a binding affinity of 1.53 × 10 3 M -1 for guanine and thymine residues in bovine DNA. Semustine undergoes major groove-directed alkylation at guanine residues to form O6-chloroethylguanine and N1-O6-ethanoguanine adducts, and generates dG-dC interstrand crosslinks. Semustine induces partial B- to C-type transition of DNA, base stacking and helical structure distortion, mild dehydration, as well as partial DNA double-strand unwinding. Semustine can be used in research related to Lewis lung cancer, leukemia, Hodgkin's lymphoma, malignant melanoma, glioma, and diffuse large B-cell lymphoma .
1
1 Cited Publications
Cat. No.: HY-W854445
CAS No.: 80081-06-7
1
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Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
Cat. No.: HY-W250111
CAS No.: 83512-85-0
Synonyms: N-Acetyl-D-lactosamine
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Cat. No.: HY-N7575
CAS No.: 21973-23-9
Synonyms: LNFP II
Category:
Polysaccharides Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer
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Cat. No.: HY-N10535
CAS No.: 82993-43-9
Synonyms: Lewis y
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Cat. No.: HY-Y0925
CAS No.: 53293-00-8
Synonyms: Hex-5-ynoic acid
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Research Areas:
5-Hexynoic acid (Hex-5-ynoic acid) is an alkynoic acid. 5-Hexynoic acid serves as a drug intermediate for the synthesis of 3-alkoxy-2-cyclohexenone .
Cat. No.: HY-W008525
CAS No.: 1109-15-5
Cat. No.: HY-21179
CAS No.: 27607-77-8
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Trimethylsilyl trifluoromethylsulfonate is a metal-free catalyst. Trimethylsilyl trifluoromethylsulfonate can be used for the synthesis of biologically active fluorinated heterocyclic compounds .
Cat. No.: HY-N10534
CAS No.: 71208-06-5
Synonyms: Lewis X
Category:
Infection Polysaccharides Animals Disease Research Fields Inflammation/Immunology Saccharides Cancer
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Cat. No.: HY-P1189
CAS No.: 154303-05-6
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Cat. No.: HY-P1189A
Category:
Natural Products Animals Metabolic Disease Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-N10531
CAS No.: 56570-03-7
Synonyms: Lewis a
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Cat. No.: HY-W033277
CAS No.: 21797-13-7
Synonyms: NSC 307191; Palladium(II) tetrafluoroborate tetraacetonitrile complex
Research Areas:
Tetrakis(acetonitrile)palladium(II) tetrafluoroborate (NSC 307191) acts as a potent Lewis acid and facilitates the formation of the 2:1 complex [Pd(1,2-bis(2′-pyridylethynyl)benzene)2](BF4)2 through the Sonogashira cross-coupling reaction.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
